one who 'tweaks balls' as in one who uses the drug methamphetamine to get amped and then shakes around and talks non-stop.
I would have asked Mary to help me study for my test but she's such a tweaker --she couldn't sit still for more than 2 minutes so that's why I got a D+
by brandon December 04, 2002
a whore, a promiscuous female who engages in sexual activity with a lot of people who they have no relationship with.
by k_milly May 11, 2009
by Dzay June 02, 2007
by Bigmike13 March 29, 2022
Someone who tinkers and adjust the setting of any object to make them perfect for their own purposes at that particular moment
by Pimpsnho's September 22, 2020
You can see a lot of these in Eugene Oregon . All though the true definition of tweaker is someone on meth but people can be on be tweakers with out meth sometime just weed and or alcohol. You will see most these people that non meth tweakers at night they smell like weed and dog shit and don’t listen to their papa. Common other name for tweaker is MILA( musty in lethal wAys)
by Lordoflandsinegpyt September 21, 2023