A variant of "slut," meaning a promiscuous female, possibly practicing unnatural sex, or gay male.  "Sloot" refers to the female variety, however.  (The practice of unnatural sex, without a display of promiscuity, is not sufficient to merit a description as either a "slut" or a "sloot."  See, e.g., "freak.")
Origins: The word "slut" is typically used to condemn the object of the description for her promiscuity and possibly unnatural sex. A straight male who describes a female as a "slut" is typically either disgusted by or otherwise angry at the object of the description. The word "sloot" is more sympathetic and merely identifies promiscuity in a female in a nongraphic, albeit dimunitive, fashion that often conveys interest in or amusement by the object of the description. It can also be used playfully as an exaggeration of a well-liked female in or out of her presence
Origins: The word "slut" is typically used to condemn the object of the description for her promiscuity and possibly unnatural sex. A straight male who describes a female as a "slut" is typically either disgusted by or otherwise angry at the object of the description. The word "sloot" is more sympathetic and merely identifies promiscuity in a female in a nongraphic, albeit dimunitive, fashion that often conveys interest in or amusement by the object of the description. It can also be used playfully as an exaggeration of a well-liked female in or out of her presence
Female:  "She is such a slut.  I don't want my boyfriend talking to her.
Female: "I hear she is such a slut in bed."
(notice inherent bitchiness)
Male: "Well, John, at least my sister isn't a fucking slut like yours!"
(notice distinct anger)
vs.
Male: "The party last night? Holy shit, there were some slOOts there."
Female: "You'se a sloooot, Angie." Angie throws a pillow at speaker, others laugh.
Female: "I hear she is such a slut in bed."
(notice inherent bitchiness)
Male: "Well, John, at least my sister isn't a fucking slut like yours!"
(notice distinct anger)
vs.
Male: "The party last night? Holy shit, there were some slOOts there."
Female: "You'se a sloooot, Angie." Angie throws a pillow at speaker, others laugh.
by Dr. Octagon January 7, 2008
 Get the slootmug.
Get the slootmug. by The Authority February 14, 2003
 Get the slootsmug.
Get the slootsmug. An attractive person (most often a Caucasian female) whom uses their good looks/sexual appeal to climb the social hierarchy.
by 123 as easy as December 3, 2016
 Get the slootmug.
Get the slootmug. by Jane_Bond October 27, 2003
 Get the slootmug.
Get the slootmug. To consistently and repeatedly purchase from Woot.com to ones mental and monetary detriment.  Action occurs pre- post- and during Woot-offs.  Often associated with sleeplessness in anticipation of a 'bag o' crap'.
by Jeremy Longbottom April 24, 2007
 Get the slootmug.
Get the slootmug. by Demonsplitz69 August 9, 2020
 Get the Slootedmug.
Get the Slootedmug.