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shotgun effect 

The shotgun effect is a term for a medication or treatment given to help or cure physical/mental illness that, in order to work, must cause harm to other parts of your body/brain. The damage done is seen as acceptable loss. Chemotherapy and some types of psychiatric medication are implemented with the 'shotgun effect'
"Oh, don't worry about Bob, he's just slobbering and gained 200 pounds because of the shotgun effect! At least now he doesn't sling crap at everyone"
shotgun effect by Scott F. December 29, 2007
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shotgun blast

A haircut that looks like you got shot in the back of the head.
Shotgun blasts on all the boys, and all the girls.
shotgun blast by Adubs April 6, 2004

shotgun shine 

Comes from the"shine" definition "to do big things". To do big things with a shotgun.
El Mariachi really had a shotgun shine when he killed everyone in the bar.
shotgun shine by kennylive November 1, 2010

Shotgun Therapy

The only know treatment for "Furryitis", Shotgun Therapy is performed by inserting the barrel of a shotgun into the Furry's mouth and pulling the trigger. Although the treatment has a 100% percent success rate in eliminating the Furry, it's Human host almost never survives the procedure. Shotgun Therapy was invented by Dr. RocketJesus666, MD, in 2010 and was first successfully preformed by him in 2011.
Bob: Hey Ted, did you hear what happened to Steve?

Ted: No, what happened?

Bob: He got Furryitis from 4Chan and had to get Shotgun Therapy.

Ted: Awww, I'll miss Steve, he was a nice guy, but I guess it's for the best.

Shotgun rider 

When you let your girlfriend sign her name in your front passenger seat binding her ownership to it so that even if you sell the vehicle the seat will be taken out and used as a redneck lawn ornament.
Jimmy: "Hey Billy Bob, I noticed that new chair ya got in the front yard."
Billy Bob: "Yup, that's my shotgun rider's seat from my old Ford pickup."
Jimmy: "Why'd ya take it out?"
Billy Bob: "She called dibs."

shotgun not 

Used to "shotgun" not doing something. Said shortly, and usually quickly, after someone asks for a task to be completed. The last person to say "Shotgun not" must then complete the task.
fathead: I got just got an oz, lets go for a session!
azz: Fuck yeah!
pedro: Got a billy?
fathead: Nah, we need to get one aye,
pedro: shotgun not
fathead: shotgun not
azz: shotgun not
spook: shotgun not...fuck it
fathead: hehe get goin spook, don't come back till you've got one
shotgun not by fatheadfm January 1, 2008

Shotgun Treatment 

Used to describe someone who is extremely manipulative, controlling, and self-satisfied, unaware their actions or behavior will eventually result in their own misfortune or downfall.
After years of beating his wife and giving her the shotgun treatment, she finally left him