Tweaking 

A crack head in withdrawal after being denied a dollar from a stranger

That white boy over there tweaking because I wouldn’t give him a dollar

Tweaking by jmusic January 29, 2020

Tweaking 

Starting unnecessary problems or arguments. Usually about a certain action of yours or as a response to something you said. Or even about something unrelated to you.

“Hey, so you still down to go out tonight?” Molly
“Dang, hold on. My girlfriend just started tweaking about how the living room is a mess.”

Tweaking by Batman in 2006 August 20, 2021

Tweaking 

To dance in a particular way referencing Bobbie Shmurda's song "hot nigga".

She tweaking hoe!

Tweaking by Bholmes_xo November 26, 2014

Tweaking 

another word for banging

We were tweaking last night and the rubber broke.

Tweaking by Brownhole24 October 8, 2010

tweaking 

Having a good time

It can be used as a substitute for "drinking", "partying", etc

Paul sure is tweaking

Oh, those fiends be tweaking tonight!

tweaking by Luov February 22, 2011

Tweaking 

When someone with a small ass try's twerking

Damn Mami that is some fine tweaking

You cant twerk but you can tweak tho

Tweaking by Blood THORNE October 24, 2017

tweaking 

To be very angry

i.e. mad, spazzing, angry

you are tweaking
Quit tweakin you tweaker

tweaking by David Fongs March 23, 2005