Rufus: I tried to set LaKeisha straight but da bitch went sista souljah on my ass.
Antionio: Damn, time to put a boot in da bitchs' mouth.
Antionio: Damn, time to put a boot in da bitchs' mouth.
by Unkkle Crakker September 29, 2006

Sista Souljah is a rap artist and was a vocal member of Jesse Jackson's Rainbow Coalition. During the 92 riots over the Rodney King beating, Sista Souljah made several racist statements encouraging senseless black on white violence. Her sound bites not only damaged her own reputation, but ultimately damaged Jesse Jackson's credibility. Presidential candidate Bill Clinton wasted no time jumping on this, and compared Souljah (and Jesse Jackson by association) to David Duke, a former Louisiana governor who was a leader in the Ku Klux Klan.
A Sista Souljah moment is when a black person damages their reputation by making a racist statement publicly.
A Sista Souljah moment is when a black person damages their reputation by making a racist statement publicly.
Kanye West had a Sista Souljah moment when he interrupted Taylor Swift's MTV Music Award acceptance speech, yanked the microphone from her hand, and declared Beyonce should have won the award instead.
by ButtSmoothie September 14, 2009

Latrell: "I hear you been poppin' LaKeisha lately. Got yo' self a soul sista I see."
Donell: "Hell naw nigga, that ho can't sing. She ain't nothin' but a BIG BITCH."
Donell: "Hell naw nigga, that ho can't sing. She ain't nothin' but a BIG BITCH."
by Nick D February 9, 2004

by herrkraft February 5, 2007

by Montyy_18 June 20, 2011

Two, or more, unusually close girlfriends. They are highly suspected of "Twizza"-ing in there spare time...
A Twizza can find love in another females eyes and not think nothing of it.
Those Twizza Sista's sure are close
Those Twizza Sista's sure are close
by CLO-Dawg August 19, 2010

Amber: Hey Brittney, you screwed Matt?!? Yay! We are Mista Sista's!!
Brittney: Ya!! I heard you did too! He was awesome!!!
Brittney: Ya!! I heard you did too! He was awesome!!!
by DURB February 19, 2015
