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An odd or ugly look directed at another person.
As a verb: "Don't you ope at me man, it's your fault you failed the test."

As a noun: "You had best wipe that ope off yo face before I bust yo kneecaps motherfucker!"
by Jt September 21, 2005
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A gimp; a wearer of rubber outfits. Origin unknown
"And hence forth Judas was cast from the group of disciples, and aloft the heavens did open and there came the voice of our Lord, and he did proclaim "Thou art but an Ope!". John Ch 7 Verse 14
by Tim Rawnsley May 11, 2004
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Ope

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I want it in the ass so hard, you do not know how much I want it.
"PLEASE I'M SO HORNY, OPE."
by Funnierman August 3, 2021
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Ope, a lady of diversity when it comes to character. Extremely patient and generous. Ope serves u based on wat u bring to d table. She's reserved, not easily manipulated. She hardly shows her true personality, but she is absolutely smart and extraordinary beautiful. Ope has that smile dat shines light at the end of the tunnel. Ope is someone that is small and portable. Ope is creative. Ope is a cool person to be with, though she can be shy at times.
#Beautiful #Smart #Creative
#BestSmile #Smallie
Ope is that one person that never gets tired of smiling.
by Unknown somebori March 28, 2017
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by brooklynT December 10, 2017
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An exclamation used by Missourians to preface a sentence. It is used in place of words "oh" or "excuse me".
"Ope, let me squeeze right past ya."

"Ope, sorry!"
by simping for sidon September 15, 2018
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What a Wisconsinite says after they fuck something up
by cheesecurdsrcool April 12, 2019
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