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Acronym; derived from "D.B."

Meaning, Dumb Bitch
"Listen Debbie, there's no retirement plans in hoe business "

"Three baby daddys and a minimum wage job says she's a deadbeat Debbie""
Debbie by cuzo steve June 22, 2016
Probably the most narcissistic person you will ever meet! She loves herself the most (more than everyone else). She is going to marry herself... In the end, she can be okay (sometimes... results may vary).
Debbie tried to write her own definition.
Debbie by Mr C June 25, 2018
OMG Debbie is such a Karen, ugh.
Debbie by Dat boy sus August 4, 2020
Debbie is a social butterfly.. confidence galore. She doesn’t spell her name with a Y coz she’s too cool to the poor excuse of a ‘vowel’. She’s an incredible lyricist and freestyle rapper. (But only when she has a few minutes to think about what she’s gonna style about). She’s a thinker and a speaker, and doesn’t shut up. Unless you tie her to a chair and beat her. Then the silence is bliss.

And that is Debbie ladies and gents.
Shut up Debbie.
Debbie by Foxtailbuttplug September 9, 2022
When someone is bringing you down, getting on your nerves with their negativity, being an all round annoyance due to their lack of enjoyment of life.
Also can be said as "Deb" "Debster" or "The Deb"
God why is she being such a Debbie?
Last night she was such a Deb.
SHe said she was going to drive us last night but then the Debster came out to play and we had to take a taxi
The Deb made an apperance last night, what a bummer.
Debbie by GreekLovers March 25, 2009
Debbie or Debbies refers to a group of girls, who all act alike, look alike, or very similar, and who blabber on about nothing we normals would care about - ie; the real blah blah blah. Debbies tend to think they are better than most ppl, walk around with a very high and mighty attitude, and love to give you looks of disgust, or 'what the hell'. Debbies are known to run in packs, or doubles. Usually Debbies are the drunk sloppy playboy wannabes at the bar.
"Look at that group of Debbies hanging off that guy.. Just so sloppy."
Debbie by ThePEnemy March 13, 2009