A somewhat derogatory nickname for the much-maligned English town Slough (pronounced Sla-ow), of which sluff is a possible mispronounciation.
"If I had the wings of a sparrow
If I had the arse of a crow
I'd fly over Sluff Town tomorrow
and shit on the bastards below" (football song)
"If you jump off at Maidenhead you can get the train to Sluff."
If I had the arse of a crow
I'd fly over Sluff Town tomorrow
and shit on the bastards below" (football song)
"If you jump off at Maidenhead you can get the train to Sluff."
by Billy-Bob McSanchez April 6, 2005

A girl/woman who is a whore or slut. One who does not care for personal well being of vagina. Dirty girl.
"Kate is such a sluff. You shouldn't date her".
"Did you hear about that sluff over there. I heard she gave a blumpkin to John"!
"Did you hear about that sluff over there. I heard she gave a blumpkin to John"!
by Alupp October 18, 2020

The act of defense in lacrosse moving towards the goalie after following the guy with the ball out of the box.
by Lax goalie May 29, 2019

by Marissa6969 August 15, 2017

Matt says: "Hey justin, Jenni is such a fuckin sluff.!
Justin says: "HaHaHa","true that"
Jenni says: "nothin"
Justin says: "HaHaHa","true that"
Jenni says: "nothin"
by matthew wuensch December 17, 2007

by Weak Thought October 15, 2010

by Quartermaster May 6, 2009
