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pneumonoultramicroscopicsilicovolcanoconiosis 

A factitious word alleged to mean "a lung disease caused by the inhalation of very fine silica dust" but occurring chiefly as an instance of a very long word. (Definition retrieved from Oxford English Dictionary)
Pneumonoultramicroscopicsilicovolcanoconiosis is notable for causing respiratory problems as well as unnecessary fatigue and frustration at spelling bees.

pneumonoultramicroscopicsilicovolcanoconiosis 

A type of lung disease caused by breathing in silica dust.

The longest word in the oxford dictionary.
Person A: Hey, guess what? I can spell the longest word ever! *Spells out pneumonoultramicroscopicsilicovolcanoconiosis.*
Person B: Dude, get a life...

Pneumonoultramicroscopicsilicovolcanoconiosis 

A medical term to describe a lung disease. Caused by inhaling very fine sand and ash. It is a type of pneumoconiosis, which also means the accumulation of dust in the lungs.
I inhaled very small silica dust from the large volcano and it caused me to contract Pneumonoultramicroscopicsilicovolcanoconiosis of the lungs.

pneumonoultramicroscopicsilicovolcanoconiosis 

1) The longest word in the english language
2) A lung disease one gets from tiny dust particles found in volcanoes
1)After I visited the volcano, the doctor said I had pneumonoultramicroscopicsilicovolcanoconiosis.

pneumonoultramicroscopicsilicovolcanoconiosis 

1. A lung disease
2. Easy way to end the spelling bee quickly
Do you have pneumonoultramicroscopicsilicovolcanoconiosis? I do and I'm suffocating or something.

pneumonoultramicroscopicsilicovolcanoconiosis 

A lung disease

Also the longest English word in the Oxford dictionary.
He has pneumonoultramicroscopicsilicovolcanoconiosis