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4-HO-DMT

4-HO-DMT, which stands for 4-hydroxy-n,n-dimethyltryptamine, is the chemical name for the drug psilocin, which is found in many species of psychedelic ("magic") mushrooms. 4-HO-DMT has a very high safety profile, there are no known overdoses that I know of (you would have to take SO MUCH).

The drugs responsible for the main psychedelic effects of magic mushrooms are psilocin and psilocybin. Psilocybin, which is 4-PO-DMT, converts into psilocin in the brain after ingestion because the molecule is too big to pass through the blood brain barrier.

Pure psilocin is sometimes obtained by synthesizing it in its pure form or extracting it from mushrooms. This is very rare and you are much much more likely to stumble upon mushrooms. An average eighth (3.5g) of mushrooms contains around 15mg of pure psilocin. So you can figure out the dose from that.

The experience usually lasts 4-7 hours total (shorter than LSD), and is characterized by laughing a lot and feeling very relaxed. There are open and closed eye visuals, pupil dilation, and a general "mindfuck" aspect to it. It is sometimes referred to as orally active DMT or long-lasting DMT.

There is always a possibility of a bad trip on 4-HO-DMT/mushrooms, so set, setting, and mindset are very important if you want to have a good trip. Just remember, no matter how "sure" you are that the trip will never end and that you are dying, it is not true. Everyone comes back.
I just took 30mg of pure 4-HO-DMT hydrochloride. That's the equivalent of around 7 grams of psilocin/psilocybin-containing mushrooms. I'm going to be incapacitated for the next 8 hours or so, so don't bug me or try to freak me out.
by Ryan/Psilocybonaut April 22, 2008
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HO De Do Ho De Do Ho De Do

The sound heard when three black guys are trying to catch an elevator.
I heard Ho De Do Ho De Do Ho De DO, and quickly hit the close button.
by Fatguyinalittlecoat December 2, 2004
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Ho dup

An extremely ghetto or redneck way of saying "hold up".
Shucks, I forgot my chaw on the tractor, ho dup.

I'ma grab my strap right quick, ho dup.

Attention train passengers, dis a ho dup!
by El Christo January 7, 2011
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ho down

Noun or Exclamation

1.) Ho down- A ho down is a ceremony in which drunken hicks run around clapping, yelling, sloshing hard liquor and banging the shit out of their siblings, all whilst listening to the shittiest type of country music

2.) Ho down- When a prostitute has been killed or injured to the point where they cannot stand nor move. Usually lying on a street corner, in an alleyway or on the bed of a SICKO!
1.) Jack and Jill were brother and sister. Jack and Jill decided to get drunk and dance a stupid jig at the ho down. The ho down resulted in the conception of their inbred child, Jilk.

2.) I still have nightmares about my time as a pimp in Toronto, losing hoes left and right. The calls of the other prostitutes "HO DOWN, OH SHIT MACKDADDY, WE HAVE ANOTHER HO DOWN!!!!!" still haunt my dreams.
by ehagh June 23, 2006
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Ho-dunk

a ho-dunk is a shitty small hick backwoods town, where theres only one or less stop light in the whole town. The villagers are hideous miscreations of God that inhabit the surrounding area, and usually helplessly addicted to crystal meth. Also everyone in town not only knows each other, but are also related in some way.
Billy Bob: wow! there's nothing to do here in this town besides freebase crystal meth and fish!
Jim Bob: yup! this sure is a ho-dunk!
by NeroKaiser July 30, 2009
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Post Ho Depression

The act of remorseful regret when a woman realizes how successful some of the nice men she screwed over have become on her way to whoring it up with general thugs, vagabonds, street hustlers, pimps, players, & dumb asses of the day. --- ASR
Would you believe Stacy is in Post Ho Depression? Yeah, she saw her ex fiance and his wife at the bank. Apparently, they bought this new big house together. Meanwhile, her baby daddy just violated his probation, again.
by The Evilness August 17, 2009
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ho-dar

A term coined by Benny from George Lopez which means you sense ho's (whores) in the vicinity.
Woah we've got a bogie on my ho-dar, 6 o' clock.
by hewhosubmitswords August 25, 2009
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