Taken literally, it is a combination of four (4) diseases,
(Gonorrhea, Herpes, Syphilis, and AIDS) and is used to describe a person, usually a girl who is known to be very slut-like and/or disease ridden.
I chose not to have sexual with the stripper because I realized that, although hot, she had gonoherpisyphilaids.
The ultimate STD originated in sherwood park by the biggest whore ever. Consists of having gonorrhea, herpes, syphillis, and aids.Thrives in the fattest smelliest greasiest whoreginas