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Cotten headed ninny muggings 

Is an insult to make the audience stare and question what you said. In other words a really akward and funny insult.
LMAO :
OMG! your a freaking Cotten Headed Ninny Muggings!

cotton-headed ninnymuggins 

dumb or foolish. ninnymuggins doesn't really have a meaning.

its a funnier way to say silly
sorry i'm late, my car was being such a cotton-headed ninnymuggins.

Cotton headed ninnymuggin 

A lazy individual who can’t pull their own weight. Calling someone a cotton headed ninnymuggin is the equivalent of calling a blacks person a Nigger.
Which one of you cotton headed ninnymuggins smoked my last pack of newports and drank my malt liquor. I’ll bust a cap in your cotton headed ninnymuggin ass when I find you

cottonheaded ninny-muggins 

What Ninja called Dr. Lupo
Dr. Lupo is a cottonheaded ninny-muggins

cottonheaded ninnymuggins

a dumb elf, as coined in the movie "Elf"
"i'm nothing but a cottonheaded ninnymuggins"
cottonheaded ninnymuggins by dfg January 5, 2004

Cottonheaded Ninnymuggins

A bafoon; someone who makes a simple mistake or falls for a childish gesture. A fool of sorts.
"Im such a cottonheaded Ninnymuggins for not realizing that!"