Up-Syndrome is when you have more than 62 chromosomes (basically being a SPED Class in one person), this usually occurs in when a male and a female have reproductive sex over the age of 50.
by The Up-Syndrome bot April 11, 2019
Get the Up-Syndrome mug."Tom came down with a case of up-syndrome soon after meeting Caroline."
"We always thought Susie was a bit weird, but we didnt know for certain until her secret reared its ugly little head -- she was diagnosed with up-syndrome."
5:00 News Report:
"Rare condition found in man with up-syndrome... Are two penises better than one?"
"We always thought Susie was a bit weird, but we didnt know for certain until her secret reared its ugly little head -- she was diagnosed with up-syndrome."
5:00 News Report:
"Rare condition found in man with up-syndrome... Are two penises better than one?"
by PetShelterPimp March 5, 2005
Get the up-syndrome mug.A person who is seriously ugly to the point no one wants to look at them without protective goggles.
by Lickle bump February 25, 2022
Get the Up-syndrome mug.1. when you have just dumped or been dumped, and you are feeling majorly low, and all you wanna do is sit around and cry and eat chocolates and strangle the teddy bear he gave you...
2. if you've just been parted from something you majorly love, and you're really down about it.
2. if you've just been parted from something you majorly love, and you're really down about it.
"dude...i'm suffering from PBUS"
"damn it! i can't believe i'm not the play is over, i'm having theatre PBUS!"
"damn it! i can't believe i'm not the play is over, i'm having theatre PBUS!"
by converse_kid February 19, 2004
Get the post break up syndrome (PBUS) mug."blah blah blah blah blah blah blah"
'Shut up! You have critical shut the fuck up syndrome right now!'
"Oh, sorry. blah blah blah blah blah"
'Shut up! You have critical shut the fuck up syndrome right now!'
"Oh, sorry. blah blah blah blah blah"
by chazwolf_ November 15, 2020
Get the Shut the fuck up syndrome mug.When a person is sick and when they go to use the bathroom to take a dump, a sudden urge of vomiting arise and with no to wipe, flush, and pull your pants up, they get on their knees and vomit with their naked butt up in the air.
My mom caught me in the bathroom with butt-up syndrome. She asked me "Saba why do you have your pants down when you are vomiting" I replied, "Because I didn't have time to wipe and pull them up!"
by Da Beast from the Middle East May 1, 2009
Get the Butt-up syndrome mug.when ur so bummed about just bein dumped by the person you loved, that you start acting like a total retard
by giz May 24, 2004
Get the post break up syndrome (PBUS) mug.