1. A word used to call your friend. First started in the 1990's, most commonly featured in the Fresh Prince of Bel-Air.
2. The guy who goes out of their way to be a douchebag. Most commonly found in the city of Guelph.
2. The guy who goes out of their way to be a douchebag. Most commonly found in the city of Guelph.
by pr0n0 September 11, 2008

That one legit drug dealer u can find anywhere with a low profile. He/she doesn't give any fucks about getting caught and they will keep going
Aye do you see that girl over their
She got caught 3 times selling drugs and she still does it
She is totally a Holmes
She got caught 3 times selling drugs and she still does it
She is totally a Holmes
by Carlosmendez May 20, 2018

1. in referance to Sherlock holmes
calling someone a smart ass or an insult in calling someone whehn they are trying to act smart and point out the ovious
2. sexy old neighbor somewhat a wigger but nonetheless a good guy with a hot superman ring.
3. slang What you could call a friend, a stranger, or use a mocking someone for being differnet
4. sarcastic comment calling someone a smart ass
calling someone a smart ass or an insult in calling someone whehn they are trying to act smart and point out the ovious
2. sexy old neighbor somewhat a wigger but nonetheless a good guy with a hot superman ring.
3. slang What you could call a friend, a stranger, or use a mocking someone for being differnet
4. sarcastic comment calling someone a smart ass
-thanks holmes (sarcastic)
-ya shut up wattson
-sup holmes?
-nm wat bout u?
-nuffin g2g tho c ya home slice
-pc easy
-ya shut up wattson
-sup holmes?
-nm wat bout u?
-nuffin g2g tho c ya home slice
-pc easy
by sexybitch May 13, 2005

A derogatory term meaning a big dick. After John Holmes the porn star. Usually confused with "homes" short for home boy or homey.
Used as an inside joke with a person who is a pest. "What's up Holmes?" Instead of "What's up you big dick?"
by Ghost of Holmes September 22, 2005

The King of Kings, God of Gods. An extremely ripped and buffed person. A natural born leader, a warrior, true fighter and most of all - The One.
by mortenh May 22, 2012

by McLoViN BiTcH June 26, 2008

The potato spelling of "homes (See: homeslice, homeboy, Better Homes & Gardens)
Person 1: Whassup, holmes?
Person 2: You're an idiot.
Person 1: Whassup, holmes?
Person 2: You're an idiot.
