What’s up brother 

A common saying/ greeting in the madden gaming community. Popularized by a streamer named Sketch. It is customary to raise you index finger while using this saying/ greeting.

Person 1: hey

Person 2: what’s up brother.

What’s up brother by PEEPEEHands04 May 6, 2024

What's up, brother? 

A phrase said as a greeting to a friend or pal.

What's up, brother? How ya doing?

What's up, brother? by JustDaryl May 21, 2024

What’s up Doc? 

Getting pegged with a carrot and then having your partner take a bite out of it explaining “Eh, what’s up Doc?”

Jessica brought a carrot into the bedroom last night. I knew instantly she wanted some What’s up Doc?

What’s up Doc? by Nomad13 June 5, 2024

What's up?

what is going on?

"Hey, what's up? I haven't heard from you in a while. How have things been?"

What's up? by Arminkshipper June 15, 2025

Say what up to John

The act of taking a huge dab to become really high

Hey man, what do you say we go say what up to John after church?

Say what up to John by Dr. Anita Cain N’Degochello September 21, 2018

Mad what up 

No lies, no cap, only real, real friends, real truth, real life, Real true friend. That’s mad what up

That’s mad what up bro

Mad what up by Broke profit May 31, 2024

oh what up son?

the typical cry of a Ford, from the 2019 game "boneworks" developed by SLZ to run on Steam VR, before being publicly executed

"oh what up son?"

oh what up son? by NOTFordBoneworks December 3, 2025