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de novo

starting from the beginning; anew
most of the malignant melanoma cases develop itself de novo from healthy skin
by YazanKoz May 21, 2016
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De whey

A meme (millennial joke) Involving a small red knuckles from the popular game franchise sonic in another virtual reality game “vr chat”. The knuckles will ask “do you know de whey” in a deep Ugandan accent.
by Archie Morrison February 16, 2018
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de-goonification

To remove any display or hint of goon like behaviour from ones sight, life, social network site etc
If you ever think after you've posted something on facebook "hmmm that was a bit goonish of me" then you need be worried about being involved in de-goonification.
I was looking through my news feed and some people's statuses have really made me consider starting a de-goonification process on my page
by Goonette23 March 13, 2011
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De-truff

To unzip and remove the lower part of a pair of cargo-trousers or cargo-pants when weather or current activities make it appropriate to do so. (See truff)
The sun has come out! Time to de-truff!
by carlbtv October 12, 2011
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De-dicked

When you RIP a mans dick off for pleasure. See "Alpha Blue"...
Dude, what did you do?
He said I had nice eyes, so I de-dicked him. He should have told me i had nice tits....
by 808-pride December 2, 2018
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de-squared

“I was de-squared by hayden
by cheekylittlerat101 February 23, 2019
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DE WAE

de wae of de deval; the ugandan people strive for dis, which pretain the 5 principles to the ugandan warrior: ONE: we sniff to identify. TWO: we spit on the enemy. 'spit' 'spit' 'spit'. THREE: we must find de queen, because she knows de wae. FOUR: we shall never freeze. people always say "freeze!" and point their weapon, but we shall never freeze. AND LASTLY, we must always, ALWAYS show dem de wae.
"I will teach you de wae; de wae of de deval"
by DA COMMANDA February 5, 2019
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