duff beer

A brand of beer drank by Homer Simpson and his friends in popular Television show "The Simpsons". It is the only drink that Moe Syzlack stocks at his tavern, Moe's Tavern.
"Hey Moe, Gimme a Duff Beer, please."- Homer Simpson
by Tuddy September 02, 2007
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P Duff

A short person of non-hispanic decent, often acts in an irrational manor. A raging homophobe/Bigot, ultra conservative;
Fights to end women's suffrage, disagrees with abortion rights. P Duff wishes to go back to the good ole days of 1843. P Duff just wants everyone to go back to where they came from.
"Oh there goes that skank ass bitch protesting against gay rights, again. Shes such a P Duff."
by IHatePaigeBuffy May 23, 2023
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duff beer

by mertyl June 06, 2003
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up the duff

To be pregnant.
It was very embarrssing for Kevin when he got Peggy up the duff, but it served him right for trying to save money by using a flak jacket.
by Dunky Oggins December 07, 2003
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DUFF cocktail

a drink spiked with roofies and viagra used by the DUFF(designated ugly fat friend) in order to get laid.
"dude dont drink that its a DUFF cocktail." "i woke up with a headace and a raging boner next to a WHALE, It must have been the Duff Cocktail."
by [THE]fixer5588 March 15, 2010
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Up the duff

Pregnant, usually unplanned.
She's up the duff and really confused right now.
by Tsee November 01, 2006
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Haylie Duff

Some rich snob prettier than Hilary Duff even though IS Hilary Duff's sister. Only popular because of "popular" sister.
by Janice January 04, 2005
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