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Short for "mother" or "mother fucker" used to show exajuration. (spelling?)
"MY TOE HURTS LIKE A MO ON HER BIRTH DAY!!!!"

"Duuudee"
Mo by jake February 7, 2005
Related Words
mo mo mo mo ho mo' po' Mo Bamba mo money mo hi mo mi mo city mo job
could mean anything. Usually used in a sentence as "You are mo" or "I feel mo" which can mean "You are gay" or "I feel strange".
I'm feeling pretty mo today.
mo by blokzberry July 11, 2006
A Mo is a codename for a morbidly obese person.
X: Hey check out that shit
Y: Yeah, thats one hell of a mo.
Mo by Mr. Twango April 4, 2011
a girl that is not extraordinarily hot but not completely unfortunate. if you're pretty bored one night, she'll do.
"Dude! that chick is hot!"
"Eh, she's mo."
mo by lani December 30, 2002
that mo sucks a mean dick
mo by your mom May 1, 2004
A Male HO or a guy who sleeps around with anything with legs, most likely for either personal gain or as a recreational sport
"Dang, that guy is a MO fo sho!"
MO by snookie007 August 18, 2009