tweaking

1. High on DXM
2. High on speed

Dude, you are totally tweaking.

by Epigone July 1, 2003

tweaking

when someone is acting a weird type of way for no reason at all.

Yo, why is you tweaking? I didn’t steal your shit.

by lilshitstain January 16, 2019

tweaking

Having a good time

It can be used as a substitute for "drinking", "partying", etc

Paul sure is tweaking

Oh, those fiends be tweaking tonight!

by Luov February 22, 2011

tweaking

To be very angry

i.e. mad, spazzing, angry

you are tweaking
Quit tweakin you tweaker

by David Fongs March 23, 2005

tweaking

an irritation, usually drug related

Man, I shot up heroin and started tweaking on it.

by suicidal.fairies July 4, 2017

Tweaking

Tripping or doing something dumb

Yo that crack head down the street was tweaking fighting the air earlier tripping

by Vito June 9, 2017

Tweaking

Somone tripping on a meth high. They are paranoid about staying up for a week straight seeing shadow people and such.

Yo that girl is tweaking yo

by BigPimppin6906 April 20, 2018