Serio

Pronounced: Se-Ree-O, the 'se' part is elongated, said with an arched brow and tilting the head back.

Meaning(s): 'is that so'; 'are you serious'

Girl: I wanna get some hubcap spinners for my focus
Guy: Serio
Girl: =\

by SaraZ May 3, 2005

serio

the state or action of complete domination of the competition.

"Jeff completely serioed the other team's defense by scoring three touchdowns"

by Edinburgh984 March 8, 2009

serio

The anithesis of a ladies man; a true man's man; magically fagalicious

Fuck you serio.

by A homosexual May 7, 2004

Serio Syndrome

To have every sexually transmitted disease at once. It thus neutralizes the infected from the affects of the various diseases. However, whoever they have sex with will die instantly.

Jeff has Serio Syndrome. He fucked Deb last night and she immediately died.

by Ridwiz October 24, 2012

serio

A bad case of crazy, obsessive, temperamental, stalker-like qualities in a person who has the physical features of a soccer mom.

Dude, my ex has a really bad case of the serio

by JonnyTroll June 11, 2010

Serio 10

n. I swear to god times 100

i like that girl serio 10

by dylannnnntizzzzzy September 30, 2018

Serio Pedo

Literal translation "serious fart"
It's equivalent in English is "real shit"

Serio Pedo, you don't have no salsa, but you're serving tacos? or
My car just broke down dude, serio pedo.

by Cheymez May 24, 2017