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Marmaduke 

1. A terrible comic, shown in many major newspapers. Has been known to ruin one's day just from a glance.

2. Anything that ruins a specific activity just from reading it.
Example 1:

Person #1 "I see you read todays Marmaduke"

Person #2 " how can you tell?"

Person #1 " you look rather depressed"

Example 2:

Every time I read her tweets it annoys me so much I close my twitter. She is such a Marmaduke
Marmaduke by Leepaul August 29, 2010
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Marmaduke 

A penis the size of a large dog, like a Great Dane.
Lil dude be dragging his Marmaduke all around the room and sheeeeeeit! Yo!
Marmaduke by Dick Dickson January 30, 2003

marmaduke 

the runt of the pack. commonly to refer to himself as 'frodo' due to lack of originality and pure BUTTERZness. can be found wanking over pictures of huckleberry with his grotty little willy.
is that a meal worm or a penis you're wanking with you disgusting marmaduke!
marmaduke by huckleberry1 July 19, 2011

marmaduke 

A euhpamism for vagina.
"For real bro, she just pulls 'em off and her marmaduke was all shaved and shit. I tore it up."

"Come on girl.. Lemme see that dirty marmaduke.."
marmaduke by d.blaze February 25, 2003

marmaduke 

A guessing game, very similar to I Spy, played by hippies while under the influence of random substances (most likely marijuana).

The item that you're guessing is called the marmaduke.

If you can't guess what it is and give up, or if someone else figures it out before you, then you just got marmaduked ...bitch.
marmaduke by kay bee November 4, 2004

Marmaduke 

Marmaduke by Anonymous March 10, 2003

marmaduke 

An Excellent band from Scotland who make concept albums
Hey, you heard the new Marmaduke Album?