Cleaning the slate is the act of getting so drunk that you wipe your brain clean of any recent information that you may have gathered. Slate cleanings are popular after big tests, projects, deadlines, or break-ups.
Josh had a really rough finals week, so he planned on cleaning the slate over the weekend to free up more space in his brain.
by mad_mike701 August 29, 2011
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To put old grievances aside and start over
guy; Hey buddy lets just wipe the slate clean , it's over.
by Goatscheese October 8, 2015
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A plan by Father Elijah to destroy the NCR & Legion,by unleashing the Sierra Madre's technology upon the wasteland,such as the cloud.
"Sources of food, supplies, medical assistance, ammo, make more collars, even print currency! Make a nation. The Cloud allows me to wipe the slate clean."
by jj_da_jet_plane January 14, 2022
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When consecutive bouts of diarrhea cause you to blow up the bathroom, leaving your bowels devoid of any contents and about as clean as they were at birth.
Person 1: Holy shit dude, you look like you lost 10 pounds.

Person 2: Dude, you have no idea. I had four massive rounds of the shits last night and only got 2 hours of sleep. I can't think of a better way to clean the slate.
by ImpDave February 8, 2016
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