to dance to hip-hop or pop music in a very sensual way typically by thrusting or shaking the buttocks and hips while in a squatting or bent-over position...while at work.
Hey Girl, you might not want to twork right now. The boss is coming this way!
one who jacksoff after they smoke meth. "Twork" comes from the way you turn the pipe side to side when you smoke meth. "Jerk" comes from jacking off. Meth makes you horny, SOMEONE WHO JACKSOFF ALOT WELL THERE HIGH on meth.