When someone is a small brain they are not smart and have the smallest of brain's. People with small brain typically are named Roger and Bo.
by WhyAPenny November 1, 2019

When taken almost literally, it means someone is unintelligent or unequipped to talk to a specific person or about a subject. Although it has ironic connotations to mean that the interlocutor or the person they are speaking with is on another level/wavelength.
Compared to my friend, big brain Bojack, who is simultaneously discussing Kant's Deontology and Quantum Mechanical superposition, I have a small brain.
by Jorolb November 30, 2020

by Queen214 November 5, 2018

Dickey Small Brains-- A fucking idiot. Somebody who constanstly partakes in fucking up. Being a clumpsy goober; acting like you know what you are talking about; being full of shit and completely believing the utterly repulsive garbage falling out of your face.
Dewayne: "All that hip-hop ruckus can suck my nutsacks"
Brad: "Did this guy just say nutsacks? As in multiple sacks?"
Ryan: "Yes, what a dickey small brains."
Brad: "Did this guy just say nutsacks? As in multiple sacks?"
Ryan: "Yes, what a dickey small brains."
by fsunoles06 November 24, 2007

Cameron's small brain is very small-minded and always focused on the stupid details he has no brains and can be very annoying most of the time
by CAMERON'S small brain October 3, 2019

Pierson's small brain is another word for a brain that has been deformed. The person with Pierson's Small Brain usually have learning disabilities and wont be able to keep up with the other kids in their school.
by heypiersonwhatsup October 3, 2019
