Similar to “whatever floats your boat” or “if that’s your cup of tea,” but with more of an supportive tone.

It can be used to encourage others to do what makes them happy or to stick to their values/beliefs despite opposition, or as a way to acknowledge others may do something differently than how the speaker/writer just said they do it and they won’t judge.
“I really want to wear this outfit I love but Sarah’s said it’s tacky.”
“That’s just her opinion! Her style is really different from yours but that doesn’t mean this style is bad. You do you, Boo! Own that look!”
-
“Personally I think that much cream and sugar in the drink makes it a coffee-flavored dessert rather than an actual coffee, but you do you, Boo.”
by Haruko-chan June 29, 2023
Get the You do you, Boo mug.
When someone does something strange, but you don’t feel like being rude and tell them. So you hit em with u do u boo
Kate: I like sniffing hair
Me: u do u boo
Kate: dies
by imtomandimcoolyeet December 26, 2018
Get the u do u boo mug.
U-Do-U-Boo Day is National Holiday that is one self chosen designated week day that falls in between the timeframes of Monday - Sunday). On U-Do-U-Boo Day, you are only allowed to cater to Me Myself & I, partake in the most selfish, self-absorbed, self-righteous, egotistical, god/goddess activities know to man on this day.

*Important note U-Do-U-Boo Day national holiday* You will still need to continue to love everyone who is special in your life but on U-Do-U-Boo Day it is mandatory that you need to love yourself more than anyone else in the UNIVERSE, that is unmeasurable, & unconditional L❤️VE to yourself!
On U-Do-U-Boo Day no one else matters more than you on U-Do-U-Boo Day!
by Bifey’s Voice May 16, 2020
Get the u-do-u-boo day mug.
Snoop Dogg’s opening line in The Pussycat Dolls’ song “Buttons” featuring snoopy.

It basically means ‘what can that ass do?’, but in an iconic snoop dogg-way
Snoop guy: ‘Damn, what a nice ass you got. What it do baby boo?’
Girl w/ nice ass: ‘A lot. Jump on that di*k for starters.’
by snappingsnoop May 4, 2019
Get the What it do baby boo? mug.
When someone does something weird, but u ain’t gon be rude about, so u hit em’ with “u do u boo”
Kate: i like to sniff hair
me: “u do u boo”
by imtomandimcoolyeet December 25, 2018
Get the u do u boo mug.
when you should do as the person says, not as he/she acts
You know she didn't take my advice, even though I told her to do as I say, not as I Do Boo.
by CvipRain October 29, 2019
Get the Do Boo mug.