GameGod22: Hey Burt, I didn't like how you said Hello yesterday
Burt: Idc I have more chromosomes then you
*GameGod22 goes crying**
*GameGod22 kills himself**
Burt: Well that's 1 less chromosome to handle!
Burt: Idc I have more chromosomes then you
*GameGod22 goes crying**
*GameGod22 kills himself**
Burt: Well that's 1 less chromosome to handle!
by BlockBoy72 July 06, 2018

Meaning you have an extra set of chromosomes. Nice way of calling someone a retard. Powerplay is a man-up scenario in sports, mostly from opposing team serving a penalty.
Person 1: "Wow, that guy is a moron."
Person 2: "Yeah, they must have a chromosome powerplay going on."
Person 2: "Yeah, they must have a chromosome powerplay going on."
by M_Dubz152 June 06, 2023

by _thememeprophet_ February 27, 2017

by Ray Flynn May 20, 2005

That one kid with Down syndrome you grew up with. The one that was sometimes too violent because he didn’t know his strength, but everyone still like him because of his earthly wisdom
by Teamumizoomi March 25, 2020

Thomas: "Ayy man, this nigga spreadin' his google chromosomes around, what we gonna do?"
Ben: "Shut the fuck up Thomas, I'm sick of your bullshit; everyone is."
Ben: "Shut the fuck up Thomas, I'm sick of your bullshit; everyone is."
by Scrötumm Teeklurr June 11, 2017
