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Chiefly biology:
Colossal Faggot Disorder is

a genetic disorder that is typically associated with sexual impotence as well as mental incompetence. The average IQ of a young adult with CFD ranges from 45-55, but this varies widely. There is a 75% correlation between CFD and Erectile Dysfunction accounting for a 10℅ margin of error.
1. There is a direct correlation between Noam's CFD and sexual impotence.

2. If that Davids kid didn't have CFD, he wouldn't have so much trouble performing perfunctory tasks such as tying his shoes.
CFD by Balsamic Vinegar November 18, 2015
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A CFD is a Crank From Deep. This acronym stems from soccer when a defender rips a shot from far out. The range of a CFD is from outside the 16 yard box to the half field line. Anything past this or closer does not qualify as a CFD.
Hey man did you see Kaplan’s CFD in the summer league game vs Strathaven?
CFD by Cfdjesus July 17, 2021
Related Words
A web3 TDL extension standing for clothing, fashion, and design. A way to be able to have a catchy website, without paying tons of money.
I just published my new website clothes.cfd
CFD by juljuljuley March 26, 2023
Carpé Fucking Diem. ... Seize the fucking day! Especially in honor of those who fight cancer with passion, humor, and love.
It stands alone as a signature or at the end of a post. CFD! "Took a glorious walk in the woods today. CDF!" or "gotta get my CFD butt in gear". "What? Your haven't registered for the marathon? CFD! "
CFD! by Julbear April 1, 2015

Communist Fondness Disorder (CFD) 

a rare disorder in which a capitalist oddly grows a fondness towards communism.
☭ I have Communist Fondness Disorder (CFD), and I am proud of it, and Stalin is to. ☭
"can't fly, dont try"

When player A attempts to fly a aeroplane or helicopter in online gaming, causing the said vehicle to crash because of lack of knowledge in flying said vehicle.

known use on the gaming software architecture "Battelfield 1942™"

in conjunction with wtbi
Phoo - "Hey OVA get in the apache!"
Rockit - "k thnx ...stop recruiting"

(crash)

QuiBill - "Hey man, im out of mans...CFDT!"
CFDT by RockitHC February 23, 2004
An abbreviation for the term 'Cat's Face Down's Face'.
It is used to describe someone who is attractive, with feline-like features (Cat's Face), but perhaps because of this also looks a bit wrong (Down's Face).

A CFDF may be a girl/boy who appears attractive in real life, but emerges as facially challenged in photographs. It may also refer to someone who is attractive in an unconventional way.
'I can't decide if Steph looks really hot or a bit demented.'
'Yeah, she's a major CFDF.'
CFDF by SilkShoe May 17, 2010