by Kemistry🌟 May 28, 2024

PGR or "Prettiest Girl in the Room" Disease is a condition that afflicts attractive women everywhere. It's characterized by the negative reaction a pretty girl expresses when she meets a girl that's prettier than her, rendering her "not the prettiest girl in the room" anymore.
Girl 1: Mandy, you look lovely as always. I'd like you to meet my friend, Sexy Withoutmakeup.
Girl 2: I don't like her.
Girl 1: You just met her, why not?
Girl 2: She's dressed like a whore.
Girl 1: Oh, you're just being jealous. You've got PGR Disease.
Girl 2: I don't like her.
Girl 1: You just met her, why not?
Girl 2: She's dressed like a whore.
Girl 1: Oh, you're just being jealous. You've got PGR Disease.
by rhastings88 March 3, 2014

The condition that a human fly suffers from.
Damn, you'd think she'd leave me alone after I rejected her 10 years ago.
Maybe she has human fly disease?
Maybe she has human fly disease?
by humanflymagnet February 8, 2010

A literature phenomenon in which the first book of a series does so well, and may even be considered a classic, that subsequent books in the series become staggeringly formulaic, to the point where the only difference between it and the last one are maybe location, names of characters, and point in time the story takes place in.
Named for Piers Anthony, author of the Xanth series, one of the most notable instances of this phenomenon.
Named for Piers Anthony, author of the Xanth series, one of the most notable instances of this phenomenon.
"I really liked Frank Herbert's "Dune". It was honestly a well written story, its just that his other books got quite... similar afterwards. Same general plot, message, almost everything but the names."
"Ah, so he contracted Piers Anthony Disease?"
"I'm afraid so..."
"Ah, so he contracted Piers Anthony Disease?"
"I'm afraid so..."
by RadienX Chaosmaker October 3, 2019

lexie: i haven’t drank water in a week but i have drank lots of milk
abi: omg lexie, you have milk disease!
abi: omg lexie, you have milk disease!
by milkymoo February 7, 2020

by BARBARAH January 6, 2022

by psendrom June 8, 2021
