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Pope-Partum Depression

When the Pope leaved your city and everyone has a hard time getting themselves back to normal
Philadelphians are experiencing Pope-partum depression after the wonderful and spiritual visit from Pope Francis.
Pope-Partum Depression by JiLo November 13, 2015

The Great Battlefield Depression 

The drop in player population in Battlefield most likely due to lack of content, boring same old maps, unbalanced weapons, bugs or repetitive gameplay.
BF fanboy: Ugh, why is BF1 so dead!
Me: It's suffering from The Great Battlefield Depression

Pummler's Depression

Pummler, a rare German species often sighted watching memes, has depression.
"Pummler's Depression really makes him sound dead inside"

Post-Coital Depression 

The traumatic realization that every girl you have had intercourse with is a nasty whore, and that every interaction leading up to and during the act was a waste of time and energy. Those who suffer from Post-Coital depression are usually attractive and presented with plenty of sexual opportunities.
Summer : Hey, what's wrong with Morty? I thought he was finally happy now that he's popular.
Rick : He finally hooked up with Jessica and is suffering from Post-Coital Depression.

yung.crippling.depression

You know Gage, the guy who's Instagram page profile pics have only been pugs? He has yung.crippling.depression

The day of Depression 

Basically every Monday...
Jack: The day of depression is coming...
Bob: Crap...