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In reference to the controversial hip hop dance motion, twerking (when one positions their back side to be the most prominant body part by squatting and arching the back, then quickly manipulating the hip joint repetatively causing the butt to shake quickly) TWERKED is the verb reference when someone who is twerking approaches another individual and directs their buttox up to the person and begins to twerk. The individual facing the dancers backside is then "being twerked".
"Dude, this hot chick came up to me on the dance floor and twerked me, then her boyfriend came and jacked me! I was just minding my business and SHE came and twerked ME - not my fault!"
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Tweaker Tinkle 

The look in someone’s eyes that lets you know that they’re a tweaker.

(Synonym for “Crazy Eyes)
Olivia: You should go for him, he’s cute!

Harley: Yeah, but he has that tweaker tinkle in his eyes
Tweaker Tinkle by harleyolivia December 26, 2019
someone who abuses methamphatamine.

usually skinny because they dont eat.
dark circles under their eyes because they dont sleep.
can harldy stand because most of their blood viens have collpased from constant injecting,

they transform themselves into a hermit-like state and keep to themselves while trying to have a normal life.
kid 1: i think that jon is using meth.
Kid2: yeah i definatly think he is a tweaker
tweaker by lovebabefor April 8, 2009
Tweaker is tayisa, someone who's a hoe
Look at that hoe Tayisa, she's a tweaker
Tweaker by Angie08 May 9, 2017
1) A speed, or meth addict who has assumed the role of the drug, in other words, they lost their personality to the drug.
2) An ex- deadhead or hippie who has fried their brain and is now living in the small, paranoid world of warped memories of a mundane adolescence. They communicate by spreading urban legends as "amazing" inspirational stories that align with their perception of reality.
3) A stupid, spastic teen (or adult, but less common) that display ignorance and naivety with every action.
I was walking through the Haight the other day and was surrounded by tweakers.

I went to my high school reunion and the tweakers were still messed up in the head.
tweaker by stv October 5, 2004
Mainly used in Philadelphia, A Tweaker is a female who gets around! A whore, smut, slut, hoe, or trick. "Tweak" can also be used in it's place, as well as "Tweaking"
Yo bul?

"Wassup with you bul?"

Shit!...whats up with Kaneisha and them?

"I don't know.....but I def heard her squad is some tweakers!"

Oh yea?.....they tweakin?

"That's What I Heard!"
Tweaker by mickey futuristic February 19, 2010

tweaker poop 

Dilapidated motorcycles, old computers, and other junk that represents a net waste-of-time and money to resuscitate for even the most skilled and diligent of DIY hackers.

In the dreamy eyes of the tweaker, however, this rusty lawnmower he found in a ditch represents an incredible sparkling opportunity to do a "fun" Burning Man project, or something of the like.

The project, however, never gets completed, and the rusty lawnmower gets stored in some community hacker's community workshop space, taking up space that would otherwise be used for more plausible projects.
"Tell Tim to stop bringing all of that tweaker poop back to the shop, I can hardly even get back to my welder without climbing over his rusty three-wheeler and the leaky row-boat."
tweaker poop by SpaceSpace August 13, 2006