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Used to mean Shut the "F" up, also means Step the "F" up.
"If you think you are man enough, then STFU and prove it".(Reference to the phrase, "Cowboy up"). Of course both phrases are commonly used together.
"If you think you are man enough, then STFU (Step The "F" Up) and prove it, otherwise STFU (Shut The "F" Up) and sit your ass down".
STFU by Cable Kenn April 10, 2006
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Shut the fuck up
to tell someone to be wuiet using profanity.
Mainly abbreviated in AIM, other chatting, and nerdy-ass, MMORPG computer games such as WoW or EverQuest
Guy 1: STFU n00b
Guy 2: I got tolded in tha hezay
STFU by Zoso_maniac February 20, 2007
abbreviation for "shut the fuck up" used when your mad at someone, their annoying, or they're talking shit
guy 1: wow your so stupid and blah blah blah
guy 2: omg just stfu
stfu by jdcblajdbaiduch January 18, 2015
Short for Shut The Fuck Up
Moana told Jason to STFU cos his definitions weren't funny.
Stfu by aanaaaa143 August 21, 2016
this means (shut the fuck up) or stuff you
"your ugly" says jill "stfu" says ally
stfu by bellialodogot October 28, 2017
Some dumbass comback a retarded kid uses when someone roasts them.
Person 1: Hey dude! Ur mom gay!
Person 2: stfu
stfu by Vorcee August 23, 2019
be quiet already (from shut the fuck up)
A: Read the article. It's no joke.

B: STFU you liar.