A racial slur against white women that perpetuates a stereotype that they're an inherently belligerent and argumentative people.
Taco bell employee: "Sorry for the wait, some Karen held up the line."
You: "That's a very racist thing to say and you shouldn't say it again."
You: "That's a very racist thing to say and you shouldn't say it again."
by Doc_Green May 25, 2023

the most BOSSIEST GIRL EVERRRRRR .....Even if u made a whole house...the karen...she would smash it with a pen tip...
hey karen! do u like the giant tv i made?
karen} it needs to be taller,colourfull ~KEEPS GOING ON~
ughhhhh the is SUCH a karen 😡💢
Karen}and a Beauty celling
...could u shut up karen
karen}SORRY STUPIDI WAS HELPING
~_~
karen} it needs to be taller,colourfull ~KEEPS GOING ON~
ughhhhh the is SUCH a karen 😡💢
Karen}and a Beauty celling
...could u shut up karen
karen}SORRY STUPIDI WAS HELPING
~_~
by YE YEEAH October 24, 2020

That P-Karen at work I've been telling you about, reported me to the supervisor for opening a NSFW link!
by Ali3n75 April 1, 2024

Karen-up or Karened-up. When a person who identifies as female morphs from a normal person to a Karen. This can mean they went into full Karen mode, made facial expressions that resembled a Karen, or otherwise adopted Karen-like characteristics. It can be an adjective or a verb.
Adjective: Courtney would karen-up her face before yelling at a cashier.
Verb: Emily karened-up her lips when she got angry in traffic.
Verb: Emily karened-up her lips when she got angry in traffic.
by Beavmetal November 20, 2023

Those psycho, loony, racist, poorly educated white women running around screaming at random people that aren't white. They are usually middle aged, has a short temper, extremely demanding, and always wants to speak to the manager. You can tell them off by their short, blond haircut.
by xxdickyboyxx June 27, 2020

Usually blonde with glasses, tries to act young but looks like they're deep into their late forties. Cries in the middle of surgery when she finds out her child got hurt on the playground and shows that awkward weakness in a professional setting either trying to gain attention or sympathy. Demands you call her Dr. So-and-so with a minor in Gender Studies while some doctors are like 'Call me Ben. Call me Josh. Call me Mike.' Her favorite cartoon character is a yellow pill with one or two eyeballs. If she asks the tech to burp the DaVinci robot and they ask her to repeat herself because she mumbles, she will email the director saying that the tech does not know how to use the DaVinci Robot.
The Anesthesiologist variant of this is the same: Blonde with glasses, never smiles with RBF and when things go down and you run your hardest to get blood from the blood bank and doing the procedure of reading the patient name, blood type, DOB and serial number three times, Dr. Karen will still think you walked and took a break.
Don't socialize or mingle with Dr. Karens. They're miserable.
The Anesthesiologist variant of this is the same: Blonde with glasses, never smiles with RBF and when things go down and you run your hardest to get blood from the blood bank and doing the procedure of reading the patient name, blood type, DOB and serial number three times, Dr. Karen will still think you walked and took a break.
Don't socialize or mingle with Dr. Karens. They're miserable.
"Dr. Karen threw a tantrum when I took only 2 minutes to get blood from the blood bank thinking I should've gotten it just like that. She's like a spoiled 5-year-old brat who wants things handed to her immediately and if she doesn't get her way, she'll throw a tantrum."
by Josephchen666 June 18, 2025

When someone is labeled as demanding, argumentative, always REFUSES to admit that they're wrong, and are overall unbearable. Due to these qualities, whoever is in this particular zone has barely any chance at getting a romantic partner or friends.
Friend: "Can you believe it?! The guy had the NERVE to Karen Zone me!"
Me: "I mean, you are a bit demanding."
Friend: "PROVE IT!"
Me: "I mean, you are a bit demanding."
Friend: "PROVE IT!"
by Hyacinthus July 11, 2022
