Sienna Syndrome is a type of syndrome where you have a crush on a girl. Once you do, you forget she is in your presence and start acting goofy, inappropriate (as a joke), and weird in front of your friends which makes you laugh. Your crush gets weirded out and there is never a chance for a second impression, though you can still come close to her if you are somewhat of her type and improve. Not guaranteed though. Men, be careful! It may be uncurable if you aren't careful and do it for long periods of time without knowing she doesn't like you for a while.
Me: *acts weird in front of friends and makes them laugh and say something just as weird back*
Crush: -in the distance- Wow, he is kind of weird. I'm going to try and avoid him.
3 MONTHS LATER...
Me: Hey -----!
Crush: Oh it's him.. Hi.
Me: *walks away* How can I make her mine?? It is so weird how she is acting
GOD: The irony is crazy! >:) He definitely has Sienna Syndrome.
Crush: -in the distance- Wow, he is kind of weird. I'm going to try and avoid him.
3 MONTHS LATER...
Me: Hey -----!
Crush: Oh it's him.. Hi.
Me: *walks away* How can I make her mine?? It is so weird how she is acting
GOD: The irony is crazy! >:) He definitely has Sienna Syndrome.
by J@cob_TRUTH February 13, 2024

by Knowledgable words November 29, 2018

When people hate on City of Boston, Boston sports, or the people in Boston every time they hear the word Boston,They get easily triggered in reality they know they aren’t winners like us.
by Khleezy June 20, 2022

The impulse or compulsion to go out and get wild on a Friday night. Not doing so leaves one with either sadness or depression
"I can't stay at home and do nothing. I need to head to the club or my Friday Night Syndrome will kick in"
by MordecaiWrote August 13, 2021

Toufis syndrome is a very rare syndrome that occurred during the late 2010s, it is the syndrome that causes you constant denial and strong opinions about topics you have no experience in
i.e I won my lane it was jungler's fault that i lost the game, excuse my delusion , i am suffering from troufis syndrome
by troufium March 22, 2021

a highly common disease amongst trump supporters and maga folks. Symptoms include believing that Trump will fix everything with the nation or lower grocery or gas prices
John scrolling through news on Facebook sees a comment on a post about gas prices
Commenter: just you wait trump is going to lower gas prices across America
John: that person probably has delusional trump supporter syndrome dtss
Commenter: just you wait trump is going to lower gas prices across America
John: that person probably has delusional trump supporter syndrome dtss
by Backstroke swimmer 24 March 15, 2025

A type of syndrome that requires one to always be in the vicinity of easily accessible drinking water.
Someone who drinks a lot of water.
Someone who drinks a lot of water.
‘Oh she’s totally suffering from mermaid syndrome.’ ‘Damn she obsessed with hydration, gotta have mermaid syndrome.’
by Genzwhsiper789 April 21, 2021
