Me:"I have this friend,and she is in world of trouble. She needs to borrow $300 to pay her rent,and I don't know how to help her"
You:"So you need money to pay YOUR rent?"
Me:"Wow,how did you know?"
You:":eyeroll:PICKING THE SENSE OUT OF THE NONSENSE is what I do,dumbass"
You:"So you need money to pay YOUR rent?"
Me:"Wow,how did you know?"
You:":eyeroll:PICKING THE SENSE OUT OF THE NONSENSE is what I do,dumbass"
by JocularC62 August 29, 2010

When May and Mary went screaming and running crazily down the street, dad muttered, "You two are out of your cotton-picking minds."
by Aura173 July 3, 2006

by Orange_cheerio October 23, 2020

by DWYCK April 12, 2007

Inmate: *drops soap*
Inmate for life with rock hard abs and biceps with shackles wrapped around him and a fucked up face: Pick up the soap
Inmate: What?
Inmate for life with rock hard abs and biceps with shackles wrapped around him and a fucked up face: I said pick up the soap
Inmate for life with rock hard abs and biceps with shackles wrapped around him and a fucked up face: Pick up the soap
Inmate: What?
Inmate for life with rock hard abs and biceps with shackles wrapped around him and a fucked up face: I said pick up the soap
by Lazar Blade March 22, 2021

Usually it's telling someone to pick up a video game controler and play, it could mean pick up a lighter and hit a bong toke though, or if you to just tell someone to do something that they should already be doing, or having been told to do it already and lack the capacity to do so themselves without being yelled at.
Person 1 : "Do you wanna play video games?"
person 2 : "Yea, sure"
Person 1 : "Well then PICK UP THEM STICKS, BITCH!"
person 2 : "Yea, sure"
Person 1 : "Well then PICK UP THEM STICKS, BITCH!"
by Tower July 10, 2007

When you’re hooking up with your chick for the 7th time after being in Texas for like a year, but then right before you bust she pulls out a Magic the Gathering deck and challenges you to a duel.
Enrique: “Yo man, what happened with playing Sea of Thieves last night?”
Bernard: “Sorry man, my chick took too long picking up the truck from Yuma.”
Bernard: “Sorry man, my chick took too long picking up the truck from Yuma.”
by Balzar Danglin June 17, 2021
