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Definitions by Aura173

out of your cotton-picking mind 

to say someone is crazy, a fool
When May and Mary went screaming and running crazily down the street, dad muttered, "You two are out of your cotton-picking minds."
Later You Loser.
My friends always use it on emails and passing notes.
You usually use it when signing off an email.
whatever. I don't really care. lyl, Sarah
lyl by Aura173 June 11, 2006