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Tumblr Down Syndrome occurs when "edgy" teenage attention whores spend all their spare time on Tumblr.

Symptoms include:
1Feminazism
2Cutting ones own wrists in attempt to appear "edgy"
3Hating on cis white males
4Believing "cis" is an insult
5Writing shitty poetry

ie:

Roses are red,

Violets are blue,

I want to kill myself.

6Listening to "obscure" bands such as mcr an 5sos
7Hating on one for having an opinion
8Creating cringey/cancerous fandoms
9Spewing bullshit via keyboard
10Pretending to be LGBT to appear "cooler"
Guy1: Hey ,You talk to that semi-gorgeous chick over there?
Guy2: Yeah, but it turns out she's got Tumblr Down Syndrome, you'll never get her.
by Ni11ioN June 10, 2016
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Churchhill Down Syndrome

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Closely related to the birth defect Down Syndrome. Which those with the condition have a widely recognized appearance. Churchhill Down Syndrome cause those with the defect to develop horse face. Symptoms vary from person to person and can range from mild to severe. Long face, buggly eyes, and protruding gums and teeth are typical signs of Churchhill Down Syndrome.
Sarah jessica Parker, Celine Dion, and Tori Spelling are examples of celebrities who suffer with Churchhill Down Syndrome.
by sinpunk August 26, 2011
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Post traumatic down syndrome - a condition that mimicks down syndrome that is directly caused by Trauma.
by Michelle Gee April 20, 2021
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Upside Down syndrome

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The disorder in which a person's Down syndrome is so severe that his face is completely rotated out of proportion. More severe cases can affect muscle girth, especially in the forearms. This renders the victim's forearms indistingiushable from pencils. One's speech may also become unamusing and trite.
Chris Max, what's up with your face?
Max BABABABAABaabaaba!!!
Chris O, you must have Upside Down syndrome, which renders yours forearms indistingiushable from pencils. My bad.
by max_fisk December 15, 2008
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Double Down Syndrome

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The listless state of consciousness experienced after eating a KFC Double Down sandwich.
Brad: "Why does Ken look like he's about to collapse?"

Trevor: "Judging by the lunch we just ate, it is my determination that Ken is suffering from Double Down Syndrome."
by Lamb Lamb April 21, 2010
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Fortnite Down Syndrome

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A person who cannot get off fortnite. If they do they will crave it until they get back on. Some call it Fortnite down syndrome, others call it being 9 years old. What ever It is I have it.
Bro my little brother wont get off fortnite!
Yeah I saw, I think he has Fortnite down syndrome!
by WiiSports April 26, 2020
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A goofy kid who resides in Basking Ridge, often found meowing after two sips of beer.
That Retarded Harry Potter with Down Syndrome was meowing outside my house last night!
by lsutigers1128 May 3, 2010
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