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If there’s a yes or no question, people usually say this if they are uncomfortable responding with yes or no. OR, someone says something to them and they feel obligated to agree and don’t want to come off as rude, but don’t actually agree one bit!
Person 1: Isn’t she sooo nice?

Person 2: I guess...

Person 1: you’re like SOOO good at soccer right?
Person 2: I mean I guess
I guess by Thegr8testputa#1 February 4, 2019
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bitch I guess 

An expression used by an individual who has been asked a question but does not know the answer.
Dude: Hey dudette, what happened in chemistry class?

Dudette:umm, Bitch I guess!
bitch I guess by PokarFace June 17, 2010

second-guess

do not second-guess my idea .
second-guess by Tallbhazzi January 27, 2019

I guess she took the kids, huh? 

"Hit or miss, I guess she took the kids, huh?"

"Shouldn't have drank too much, I guess she took the kids, huh?"

anyone's guess 

To be of a questionable nature; something uncertain.
1) Exactly how someone as disorganized and ill-tempered as Joe got the job is anyone's guess.
anyone's guess by VAKI5 May 10, 2005

I Mean I Guess 

A half-hearted yes, or simply agreeing with someone for the sake of responding.
Victor: If you say "I mean I guess," one more time, I swear I'll stop talking to you.
Kaylee: I mean I guess.

history of the entire world, i guess 

the absolute best video to watch right before you have an exam on world history... it saves lives
DUDE ONE: did you know that the sun is a deadly laser?
DUDE TWO: not anymore because we have a blanket
DUDE ONE: history of the entire world, i guess