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A hug (or cuddle). The original Dutch word 'knuffel' was deemed to be English sounding enough to be fully incorporated. Knuffle sounds the same and means the same.
I gave janet a big knuffle during the full moon.
knuffle by StartRunning March 30, 2010
Related Words

Knuffler 

The master of seat sniffing, knows all the vintage smells and flavours and can distinguish the scent of multiple ethnicities. Has a particular Penchant for sweaty crack - prefers males
Knuffler extraordinary, Liam Johnson, considered to be the founder and master of knuffling, is a true knuffling professional, bouncing around the office from one cubicle to the next
Knuffler by Ruby miner September 12, 2020

Knuffle bunny 

A bag of dope that is jettisoned in response to approaching authority figures and is later recovered or serendipitously discovered by another drug user. Knuffle bunny habitat includes city parks and playgrounds.
On her way to school Jane spotted a fat Knuffle bunny in the sand under the slide.
Knuffle bunny by charlesmarx September 15, 2009
An outward exhale through the nose in response to something slightly humorous.
Nathanael while scrolling through tiktok, knuffled every so often when the memes were 🔥🔥🔥
Knuffle by TheRaptorCometh December 14, 2022

knuffle bunny 

a sexual act which entails smearing large amounts of feta or blue cheese on ones hand. you then eventually insert that hand into the anus of your lover while engaging in hetero sex in the doggystyle position.
Oh, when that girl is in the mood, I pull the Knuffle bunny on her.
knuffle bunny by biggityowns December 17, 2008
When you rub your head against your puppy’s head.
Jack: why are you rubbing your head against your dogs?

Jeff: my dog loves when I knuffle him.
Knuffle by makerbayfield December 30, 2019