To intentionally interfere with another's process, practice, method, or effort to accomplish some specific goal. The use of this is tied to Stanford University and its Comp Sci department as part of their interaction with Military and Intel people. In Stanford Lingo to RF someone is to stomp them into the dirt - make their effort worthless and to intentionally discredit them in the public. Stanford members are famous as well for RF'ing any number of people.
To be very, very, very drunk. Intoxicated to the point of no return. When a said person is "rat fucked", common aftermath includes sever headache, embarrassing flashbacks and an inability to remember anything from the period that the said individual was "rat fucked".
Geez man, I got rat fucked last night.
Tonight, we're gonna get rat fucked!
Dude, I hooked upwith that girl,but she was rat fucked.
I'm not going out with your mates, all they do is get rat fucked.