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To accelerate through first base (french kissing), onto second base ("heavy petting") to third base (oral sex) and finally coming around to home plate (sexual intercourse).
Wow, hit a home run with Sheila tonight, gimme a high five Barry!
Home Run by Cayle Funck October 10, 2003

Lucky Home Run 

When guys, or girls, brag about getting a lucky home run, they ain't talking about baseball. They're usually referring to how they ran through the bases on a one night stand; First base, Second base, Third base, Fourth base, and yeah, that's right, Fifth base, baby! ;)
Guy 1: Dude, i just ran a Lucky Home Run: on the first date!
Guy 2: Sweeeet!!

home run derby 

An orgy, or any occasion where lots of sexual intercourse is being had.
Last night's home run derby really tired me out, that was a lot of scoring!
home run derby by rhank April 15, 2008

Home Run Derby 

MLB competition held every year in the All-Star Break. Usually consists of sluggers such as Jose Bautista and Mark Trumbo. Prince Fielder was the 2012 champion.
MLB Home Run Derby All-Star Break Jose Bautista Mark Trumbo Prince Fielder
Home Run Derby by rickyony November 17, 2012
completely fucking blacking out from anything past advil
Tad: Chad just hit a fucking home run!!
Brad: should we help him?
Tad: put him in bed and let him sleep it off.
chad was not fine. RIP
home run by ongekyume September 16, 2019

Walk-Off Home Run 

A term in sports lingo that has gotten completely out of control. Originally coined by Dennis Eckersley in 1993 to describe a home run of such power that you don't even turn around to look ... you just walk off the mound.

The corny fools at ESPN - and their brain dead followers - now use the term to decribe virtually any play that ends the game; walk-off hit, balk, double, single, etc.

"Game-ending" and "Game-winning" have surrendered.
If we use the term "Walk-Off Home Run" why not ... "The Mets lost in the bottom of the 10th on a walk-off groundout."
Walk-Off Home Run by Trendon July 20, 2009