A term that started from an Instagram post by the account “@rap” about Tony Hawk selling blood-infused skateboard where the famous rapper Lil Nas X commented “nah he tweakin.” Lil Nas X was annoyed that Tony Hawk wasn’t slandered for using blood in a product while the rapper was, in his custom shoes. The term spread like wildfire across Instagram.
in English it means "no,he is presumably high on methamphetamine." A person of color says "nah he tweakin"when referring to a skinny white person that did something they don't like. Just like a white person says "No thank you! Hes smoking crack" to a skinny black person.