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When someone spends too much time in a shower, bath or swimming pool and ends up with soft, wrinkled skin. This then leads to the person looking like a Prune, hence the term.
Person 1: Man, that was a well deserved bath!

Person 2: I can tell - you're Pruning all over!
Pruning by Grbel08 August 16, 2011

Friend Pruning 

The act of removing multiple friends on one's friend list on social networking sites such as facebook and myspace
Why does Susan have less friends than usual on facebook?
Probably just doing a routine friend pruning on the people she doesn't like.
Friend Pruning by Ben Fong March 3, 2010

Pruning the Hedges

The act of trimming your overgrown pubic hair
Tim: I just pruned the hedges. Phew, I really needed that.

Rob: What do you mean, pruning the hedges?

Tim: Look! See? I even made an arrow with it!

Rob: Dude, put that away! Nobody wants to see that!

Dude Pruning 

Hardcore manscaping. Male hair removal/control/abatement.
Someone should tell Captain Eurospeedo to schedule a dude pruning before going out in public.
To suck in your poop in your butt by pushing the poop inside before it comes out.
I am purning because im in a court while playing basketball.
Purning by butt face fred October 3, 2007
To trim branches or twigs off a tree or plant
Swing Ricky, swing! your a monkey and your pruning the tree! Your a monkey pruning!
pruning by Chris Graham January 29, 2004