A combination of Herpes, gonorrhea, syphilis, and aids. Usually the first thing someone thinks of when they think about a really slutty girl/guy they don't like.
A term referring to the many STDs you might acquire from an innocent act like sharing a dryer sheet in a community laundry room, or sitting in a public hot tub or steam room, or using a public toilet.
Man, I found a strange dryer sheet in my clothes again. I hope I don't get Herpagonnasyphillaids from that shit.