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1. Referring to society's addiction to and overuse of BOTOX, a substance injected into the facial muscles (typically frown lines), paralyzing them in order to prevent wrinkles from forming.

2. The unnatural appearance of the face from overuse of BOTOX.

3. In reference to Botulinum Toxin - where BOTOX gets its name. Main cause of food poisoning, this toxin is known to spread throughout the body after injection and may cause serious complications and may be fatal.
Many Hollywood actresses are so botoxic that their faces are in their 30's but their necks are in their 70's.
Botoxic by BratQu September 7, 2009
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Botoxic shock 

The look of permanent suprrise that results from one-too-many injections of Botox or Restylane.
Susan's botox treatments have made her look not younger, but perpetually astounded. She always looks as though she walked into a huge surprise party, or woke up next to a wildebeest. She has a serious case of botoxic shock.
Botoxic shock by rococo March 13, 2010

Botoxic Bitches

A group of highly fake in appearance bitches who pretend to like each other but won't hesitate to stab each other in the back if it made them look better...
These botoxic bitches will cancel themselves out in the end
Botoxic Bitches by Catmandue March 2, 2019

botoxicated

adjective - describes a person whose skin shows obvious overuse of Botox
Wow look at that woman! She thinks her skin looks so young, but it's so obvious she's totally botoxicated!
botoxicated by nekochan52 October 3, 2008

botoxicated

The result of having too much botox injected in the small facial muscles, resulting in the inability to change expressions.
"I really think your joke is funny, I just can't smile. Just got back from the dermatologist's office and I'm really botoxicated" or "She's so botoxicated she can't even blink"
botoxicated by wrightw1ng September 19, 2009

botoxicity 

The physical changes that occur when a patient has recieved to much BOTOX and they become freakish looking .
Nancy Pelosi and Mickey Rourke are suffering from a serious case of Botoxicity.
botoxicity by Ofashea November 5, 2020

Botoxicologist 

Someone who is a professional botox administrator, giving best results.
Them: Who did your botox?
Me: Gideon Archey, shes the best botoxicologist I've known!