OwO 

A disease originally caused by Furries, and Weebs. It is currently the most infectious disease spread by furry to furry, and weeb to weeb.

Person 1 - Nice cock OwO

Person 2 - Kill yourself

OwO by SmexyCentari April 29, 2020

OwO 

We all have said it at some time but in all honesty it is a surprised cat

OwO what's this

OwO by I_am_your_gay_mom February 13, 2019

OwO 

Best way to show that you're a furry.

You : Yo what up.
Furry : Hewwo OwO
You : BEGONE MOTHERFUCKER

OwO by idontreallyknowtobehonest December 31, 2018

owo 

OwO is a phrase used by furies and gamer girls. OwO means "What's this?" and is used over 500 times a day.

Furry/Gamer Girl: hehe owo

owo by Informatious December 26, 2018

owo 

Oral Without (condom)

John and Susie decided to have owo.

owo by lightspeed15 November 11, 2011

OwO 

terminal brain cancer

owo gives cancer

OwO by UwU_68 October 14, 2018

OwO 

you gay ass weeb

John: I wanna slap that ass!
Terry: OwO

OwO by @Jesus February 26, 2019