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Stands for "My Life Sucks Right Now", a more mature and considerate way of saying "FML". No life should or deserves to be "F"ed.
Kevin: "Omg, FML. I'm out of milk for my cereal."
Kiana: "Don't be so immature. No life should be 'f'ed. You should instead say your life sucks right now."
Kevin: "Okay then. MLSRN. I'm out of milk."
MLSRN by Huynher October 21, 2010
Related Words
MLS mlsme MLS Lifer MLSA mlsakis MLSB Mlsd mlsDma MLSE mlsek
Acronym for My Life Sucks Balls.

generally used when life is stressed and nothing seems to make sense.

It is a cry of depair.
Jack: How are you Shibin?
Shibin: MLSB Bro!
MLSB by humanwiki September 29, 2010
Initials of Mobile Life Support Services, the finest group of Emergency Medical Technicians and Paramedics , as well as Dispatchers and ancillary staff in the entire Hudson Valley and maybe even the east coast. Often referred to THE paramedic ambulance.
MLSS responded quickly and saved the women's life.
MLSS by bosstothebest February 2, 2010

mLSSStress 

Handle for an individual female gamer, known for her activity within fps circles, specifically Call of Duty for XBox360. Also known for founding the first co-ed Gaming Community Administrated primarily by women gamers. Nickname 'mistress' coined by gamers along with 'the dominatrix' after she became ranked in the "Domination" game mode.
Didn't you see that gameplay comedy skit mLSSStress produced? It was a bunch of gamer chicks in kitchens on Call of Duty maps RPG'ing noobs as they walk in. I LOL'd
mLSSStress by HLKHW July 21, 2010
Maple Leafs Sports & Entertainment is a professional sports company with its headquarters in Toronto, Ontario. Valued at 1.75 billion USD, they have many assets including the Toronto Maple Leafs, the Toronto Marlies, the Toronto Raptors, the Toronto FC, and the Air Canada Centre.

Unfortunately (or fortunately for their competition), they are 80% owned by the Ontario Teachers' Pension Plan, who don't give 2 sh*ts about sports, except to collect their pensions and go to sleep every night laughing at how much the Leafs, the Raptors, and the FC fail year after year.
Justin Bieber is a disgrace to music as MLSE is a disgrace to sports.

If MLSE got $1 from every person in Toronto every time one of their teams made the playoffs, MLSE will have $0.

The amount that MLSE cares about its teams can be compared to the amount of success Ron Wilson has as a coach, which is negative infinity.
A dark place in the void with no escape and infinite pain without end the only person known to survive this place was chuck norris
Mlsek AHHHHH**HHH** HHHHHH*HHHH*