LMSO 

"Laugh my shit(s) out."

Person 1: I collect my boogers in a Ziplock bag.
Person 2: LMSO!

LMSO by cheeeeezystix March 20, 2010

LMSO 

Abbreviation for Laugh my Scrotum off

Bob~ "Hey dude, remember that funny thing i did last night?"

Jack~ "yeah, LMSO"

LMSO by A7Xrules112 January 7, 2011

lmso 

Laughing My Socks Off

A politer way of saying "lmao"

Jake: Did you hear? A cat lady moved down the street!

Tom: LMSO!

lmso by Neko-chan December 24, 2007

lmso 

Laughing My Shit Off:

When you have a little piece of crap dangling from your rectum and you laugh to get it to fall.

I spent over twenty minutes on the toliet laughing my shit off.

lmso by chaoskron May 6, 2004

LMSO 

Laughing my shirt off.

GUY 1 (after seeing a funny picture): LMSO! …laughing my shirt off.

GUY 2: Too bad you're not a buxom female.

LMSO by themagicalnegro May 19, 2010

LMSO 

Laughing my shirt off - a variation of LMAO. Often followed up by "AFITAC!" "and feeding it to a cow!" as popularized by the British gangsta-gypsy-rock band Larrikin Love's song On Sussex Downs.

Ed is so Rubbish that I was LMSO AFITAC!

LMSO by K8 'n' Sandy January 14, 2007

lmso 

When one laughs their shit out <3

" hahahaha i think i just laughed my shit out "
" wow my shit has been laughed out "
" let me check, i think i shit my pants "
" lmso mayyyyne "

lmso by Latique January 6, 2008