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protest fatigue 

The exhaustion and frustration that comes from protesting and marching for a cause that never seems to be rewarded with concrete results. march, protest, movement, revolution, justice, peace, racial justice, women’s issues, women, African-American, white supremacy, NAACP, Charlottesville, Black Lives Matter, Tiki torch, KKK, skinheads, President Obama, President Trump, Trumper, Trumpism, Trump army, silent majority
I know there is another march this weekend, but I’ve got serious protest fatigue. We have been marching for 5 years and nothing has changed.
protest fatigue by joecoolthefool October 2, 2017
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Chronic Fatigue 

Being in a state of sleepiness or extreme exhaustion after smoking some bomb green.
"Look at Eelander over there man, why's he so sleepy all of a sudden? that was good shit." Must be that "Chronic Fatique" that got a hold of him. "CF, what's that?" "Chronic Fatique"
"Chronic Fatigue"
Chronic Fatigue by Tracy McBert January 2, 2012
A group of fat people.
"that fatigue needs to go to subway not golden coral"
fatigue by Clop Placrid March 2, 2007

adrenal fatigue

Adrenal fatigue can be from dehydration. Symptoms include
1. Craving for salty foods
2. Craving for sugar
3. Thirsty for plenty amounts of water
Adrenal fatigue may also correlate with your blood pressure.
"I feel dizzy I need some water I think I may have adrenal fatigue"
An extreme tiredness felt by obese cunts when they try and undertake physical exercise.
"I tried to do 20 minutes on the treadmill, had to stop after 10, due to the fatigue..."
Fatigue by Bayesoir December 31, 2019

Trans fatigue 

Refers to growing annoyance expressed by public towards trans activists.
Majority of the public have got trans fatigue
Trans fatigue by AnonDoxy June 2, 2023

Chronic fatigue syndrome

Difficulty waking up, or doing much of anything, resulting from smoking too much Chronic. (High THC marijuana Bud. The "good" stuff)
Q: "What is with me these days? Why are my eyelids like lead weights, and why am I still in bed at 1pm? I've got sh*t to do ... um, where's my bong?"

A; "Its all that bud-smoking, yo! You've got Chronic Fatigue Syndrome.