ISO 

A competition of one-on-one in any type of situation, sports, fights, tacklezone, etc.

Justin: Paul, i own you in basketball!
Paul: Ok, Justin, ISO right now, i will nut on you.

ISO by EWIED May 22, 2009

iso 

Taken from the basketball term for an isolated 1v1. Used when talking about someone's ability to pull bitches and talk to them one on one. Synonym of "Rizz".

Person 1: Did u see ben try to talk to that girl? She turned away the moment she saw him.
Person 2: That munch got ZERO iso

iso by iso king September 3, 2022

ISO 

1) In "TRON: Legacy", ISO is an acronym for "Isomorphic Algorithm", a life form that spontaneously emerged, without planning, from the conditions that existed in the grid at that time.

2) A term for a really really hot chick. This is adapted from the 2010 film "TRON: Legacy" because Quorra, the last ISO played by Olivia Wilde, is so unbelievably hot.

Guy 1: "Damn, that chick over there is so hot I would let her eat crackers in bed."

Guy2: "Yeah, she's such an ISO."

ISO by Husky Balls December 30, 2010

Iso 

Short for "i seek out"

ISO a new wife

Iso by pbr121 February 20, 2018

ISO 

An abbreviation for specific Asian/English phrasiology, meaning: "I am so..."

Often used, as in, "OH, ISO HORNEY!"

ISO by Richie333 December 24, 2008

Iso 

Isolation. When you get coronavirus and you have to quarantine until you're recovered.

"I got covid so now I'm in iso for a week"

Iso by Lord of Losers March 30, 2022

Iso 

Also means the basketball term for a ISOlated 1v1. Main meaning: Someone's ability to pull bitches and talk to them one on one. Synonym of 'Rizz'.

Person 1: Did you see David trying to approach the girl in the cafe? She turned away and ran the moment she saw him.

Person 2: That guy has ZERO iso.

Iso by boppy32 September 5, 2022