to have sexual relations with; often used when asked if you "know" somebody. if you know someone in the biblical sense, you have had sex or sexual relations with them.
mike: so, how well do you know amy?
tommy: well i don't know her in the biblical sense or anything, but we've hung out a few times.
a popular phrase used when playing an FPS such as Halo, Call of Duty, etc. It can only be used when getting multiple kills in a row. A Term made popular by ELPRESADOR from youtube.